NeuroLog System
Application Notes

NeuroLog offers a variety of amplification modules that are used to make microelectrode recordings (intracellular or extracellular), EMG/EEG multichannel recordings, or for use with strain gauge or pressure transcuders.

Extracellular AC recording setup with spike discrimination and audio monitoring.

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   Modules Used: NL100AK, NL104A, NL106, NL125, NL201, NL120S, NL985S

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NL100RK – Record from and then electrically lesion your recording site without moving or disconnecting the electrode. 

   Modules Used: NL100RK, NL104A

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Avoid grounding loops when when recording from more than one NL100AK AC preamp head stages. 

   Modules Used: NL100AK (2 or more)

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Typical setup for intracellular (DC) recording. 

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   Modules Used: NL102G, NL412, NL125, NL106, NL304, NL405 x 2

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Four channel isolated amplifier setup with signal conditioning and filtering. 

   Modules Used: NL844, NL820A, NL135, NL144, NL530

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NeuroLog setup for measuring physiologicial pressure. 

   Modules Used: NL108A and others NL108T2, NL108T4, NL108L2, NL108L4, NL108D4

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Triggering Stimulation & Pulse Generation

If complex pulse protocols are required with full control over the timing characteristics here are some of the NeuroLog solutions. The pulses can trigger other equipment like electrical stimulators. See the electrical stimulation section for other pulse generation protocols that feature stimulation.

Triggering stimulation at a specific time after a planned number of pulses within a burst. 

   Modules Used: NL304, NL405 x 2, NL301, NL603

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Controlling burst duration and repetition as well as output frequency and width with a set number of burst of pulses. 

   Modules Used: NL603 x 2, NL304, NL405, NL301

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Controlling burst duration and repetition as well as output frequency and width with a regular burst of pulses.

   Modules Used: NL304, NL405, NL301

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Stimulation triggering with a set time after EMG activity. 

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   Modules Used: NL703, NL201, NL405

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NeuroLog versatility with stimulation timing protocol – Set the number of trains, bursts in a train, and number of pulses in a burst.

   Modules Used: NL603 x 4, NL304 x 2, NL301, NL405

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Controlling burst frequency, pulses/burst, pulse width and frequency in a regular burst of pulses.

   Modules Used: NL301, NL304, NL603, NL405

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Signal Conditioning Filtering & Processing

NeuroLog offers modules for single and multi channel filters and signal conditioning to remove unnecessary frequencies and components from biological signals prior to their acquisition. Some of them can even be used to help with simply processing needs.

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Connecting four filters between an isolation amplifier and a signal conditioner.

   Modules Used: NL820A, NL125 x 4, NL530

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Incorporating an analog output to monitor instantaneous intervals between an irregular set of input pulses.

   Modules Used: NL304, NL601

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Electrical Stimulation

NeuroLog offers a battery powered constant current stimulator which can be used in conjunction with other NeuroLog modules. Plus, the output pulses of the NeuroLog system can trigger other laboratory stimulators.

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Simple stimulator circuit samples.

   Modules Used: NL800A, NL510A, NL512, NL405, NL301, NL304

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How to use a single trigger pulse to produce two stimulus bursts from two stimulators with a variable delay between the bursts.

   Modules Used: NL405 x 3, NL301 x 2

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Bi-phasic pulse generation of a defined duration burst. 

   Modules Used: NL301, NL405 x 2, NL506, NL510A, NL800A x 2

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Generate an isolated biphasic voltage output using a biphasic analog waveform with two NL800 constant current stimulus isolators. 

   Modules Used: NL512, NL800A x 2

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Produce pairs of pulses with interval control from a single trigger input (i.e. NL301 Pulse Generator) using a delay/width module and a logic gate module. 

   Modules Used: NL301, NL405, NL501

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